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(1996) cloned dystrobrevin. the biggest ORF in the dystrobrevin gene demonstrates 50% homology to the cysteine-abundant and C-terminal domains of dystrophin, and eighty four% homology to the phosphoprotein located in the electric organ postsynaptic membrane in Torpedo californica. Five unique mRNA transcripts had been preferentially expressed in numerous tissues.

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Two alternatively spliced exons (exons 11A and twelve) are used solely in striated muscle mass. A comparison with the genomic Corporation of dystrophin and dystrobrevin confirmed the two genes have considerable similarities of their genomic structure, implying an ancestral or evolutionary marriage.